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For example, the logistic equation (Y=1/(1+e ^ (- k (t-t0))) has been shown to best fit the in vitro release curve of tadalafil particles (R =0.9942), where k is the release rate constant and t0 is the release midpoint time
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43 Phenolics indirectly reduce fatty acid synthesis by inhibiting lipid-metabolizing enzymes such as fatty acid synthase and acetyl-CoA carboxylase, as well as lipogenic transcription factors
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