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Both turmeric and curcumin were safe for human use, particularly when taken orally

Effect of exercise on diabetes-induced oxidative stress in the rat hippocampus

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Interestingly, free glutamine and glutamate have been shown consistently to influence these processes, by various mechanisms which are further explained in the following sections

Conceptually, this makes sense because as these intermediates are used as precursors for biosynthesis of macromolecules, they concomitantly generate NADPH to drive the biosynthetic reactions thermodynamically