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Surg Endosc 27(3):709718

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GLP-1 analogs are safe, well tolerated, resistant to desensitization and well characterized in the clinic

[59] reported that individuals at stages IIIV of chronic kidney disease exhibit significantly reduced urine levels of S-adenosylmethionine and SAM/S-adenosylhomocysteine ratio, as well as a decreased cysteine/homocysteine ratio in blood plasma in comparison to patients at stage II of CKD