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Biophys Rev 13(2):259272

If you currently inject on Monday mornings and experience peak nausea TuesdayThursday (your workweek), shifting injection to Friday evening moves peak symptom days to SaturdaySunday when you have more control over meal timing, physical activity, and rest

Common side effects like nausea, vomiting, and diarrhea remain, and long-term safety for brain protection needs more study

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The dopamine connection Tirzepatide acts on both GLP-1 and GIP receptors