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Eventide was an injection-free GLP-1 agonist that showed promise, but ultimately didnt get FDA approval for its application to treat type 2 diabetes

GLP-1Rs were expressed in five of six skin biopsies from psoriasis plaques, in one of six biopsies from unaffected psoriatic skin, and in one of six biopsies from healthy skin

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and TCF7L2 is linked to glucose homeostasis and metabolic signaling

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