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Vitamin C is a reducing agent capable of rapidly eliminating reactive oxygen species (ROS), it also works as a pro-oxidant antibacterial molecule, potentially altering the antimicrobial efficacy of some antibiotics by two proposed mechanisms: I- the transfer of vitamin C into bacterial cells, which results in the synthesis of H2O2 and, as a result, ROS

Microfluidic based models also are designed to include the stress of the blood flow in BBB physiology but also closer replicate BBB structure with thicker membranes [117]

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Gupta NA, Mells J, Dunham RM, Grakoui A, Handy J, Saxena NK, Anania FA