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The interest is legitimate and the animal data is compelling, but intellectual honesty requires acknowledging that compelling animal data has failed to translate to human benefit in many prior pharmacological contexts

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Anything involving dose or timing is a clinician-led decision

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No proven upside to offset even mild risk: When benefit is uncertain, small and infrequent risks matter more Lipo-C should not displace interventions with strong outcome data (diet, activity, and, where indicated, approved pharmacotherapy)