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In the largest and longest follow-up study to date (up to 12 months), patients with mild AD underwent FUS targeting the hippocampus, frontal, and parietal lobes, with no serious adverse events, full BBB closure within 48 h, and cognitive outcomes comparable to those seen with natural disease progression (Rezai et al., 2022)

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Where These Numbers Come From The community doses are extrapolated from a large body of animal research

Although in vitro studies of the injured peripheral nerve suggest a role in neuronal regeneration, neurotrophinsBDNF and N/T-4/5 in particularhave the ability to bind both growth-promoting and growth-inhibiting receptors

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