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Prior Authorization Requirements Even if covered, insurers typically require: BMI records over time (showing persistent obesity or weight-related trends) History of prior weight loss attempts, including lifestyle programs, diets, or medications Physician notes establishing medical necessity, explaining why tirzepatide is appropriate 4

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If side effects don't resolve within 6 to 8 weeks despite management strategies, consulting your PlexusDx provider about alternative peptide compounds like tirzepatide may be beneficial

Obesity Is a Chronic, Hormone-Driven Disease