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3235 To provide some context, a weight loss of up to about 5% was seen with 4.5 mg of dulaglutide, 7.2% with 2 mg of semaglutide, 10.6% with 2.4 mg of semaglutide in adults with overweight or obesity and T2DM (STEP 2), 35 and 12% with 15 mg of tirzepatide, following treatment periods of 40 to 68 weeks