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The primary mechanisms of action include: Appetite suppression GLP-1 agonists act on receptors in the hypothalamus to increase satiety and reduce hunger signals [21] Delayed gastric emptying slowing the rate at which food leaves the stomach, prolonging feelings of fullness Improved insulin secretion enhancing glucose-dependent insulin release from pancreatic beta cells Reduced glucagon secretion decreasing hepatic glucose production Whilst GLP-1 medications do not directly increase basal metabolic rate, they influence energy balance through reduced caloric intake

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An emphasis on improving overall nutritional status rather than taking isolated zinc supplements is advised

& Tolmunen, T