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Intranasal BBB bypass is a validated human pharmacological route actively used for other biologics (e.g., intranasal oxytocin and insulin)

Etrolizumab for maintenance therapy in patients with moderately to severely active ulcerative colitis (LAUREL): a randomised, placebo-controlled, double-blind, phase 3 study

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[138] indicated that Panax ginseng could correct behavioral deficits in ASD offspring of Valproate-exposed mice, improving marble burying, sociability, locomotor activity, and spontaneous alternation, suggesting therapeutic benefits for neurodevelopmental disorders like ASD

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