cons of retatrutide Diagram showing the mechanism action of retatrutide pros and cons Half

While direct causality in humans hasnt been demonstrated, these agents are contraindicated in people with a personal or family history of MTC or multiple endocrine neoplasia type 2 (MEN2)

I gave Hormone Harmony a go for the past month

An imbalance in estrogen and testosterone levels can lead to the formation of breast tissue within the male breast, a condition known as gynecomastia

While clinical trials show adults on the highest dose of Zepbound lose an average of 22.5% of their body weight after 72 weeks (when paired with diet and exercise), recent Phase 3 trial data (from the TRIUMPH-1 study released in May 2026) shows even better results

Current medical guidance treats obesity as a chronic condition, and long-term or indefinite semaglutide use is considered appropriate for patients with ongoing obesity-related health conditions

Their findings, however, proved inconclusive