Available at: PubMed Cerovecki T, Bojanic I, Brcic L, et al
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While responses to incretin-based therapies vary across cancer types, analysis of existing data reveals several shared mechanisms that may explain their particular potential in obesity-associated cancers: i) Direct metabolic intervention: Tumor cells, particularly those evolving in an obese microenvironment, may exhibit heightened sensitivity to alterations in metabolic conditions
Cullen KM, Kocsi Z, Stone J
The post reports that placebo groups lost 2 to 3 percent of body weight, and uses that contrast to argue the medication is doing real work rather than the surrounding study conditions