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Lipogenesis Inhibition: In adipose tissue, NNMT inhibition reduces lipid accumulation by up to 70% (in vitro), shifting the cell's priority from fat storage to energy expenditure

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NNMTi-mediated changes to the availability of nicotinamide/nicotinic acid in conjunction with the presence of moderate amounts of Lactobacillus may promote a positive feedback loop further increasing the abundance of Lactobacillus

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