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1 Introduction Osteoarthritis (OA) is among the most prevalent degenerative joint diseases globally, affecting more than 500 million people worldwide and ranking as the leading cause of disability among adults aged 50 years and older ( Ferroptosis, first reported in 2012, is a novel form of cell death distinct from classical apoptosis, pyroptosis, and necrosis ( Due to the possible critical role of ferroptosis in OA, there has been a surge of interest in elucidating its molecular mechanisms and exploring potential therapeutic strategies

Each case is unique, and prognosis depends on factors such as the extent of initial damage and how quickly treatment was initiated

Fibrogenic Effect of Oxidative Stress on Rat Hepatic Stellate Cells

THCV, by contrast, supports the body's natural regulatory systems without creating dependence

Zhang C, Ni X, Konopleva M, Andreeff M , Duvic M

When weight loss happens more gradually, the body tends to preserve more lean mass