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The impacts of BPA were more prominent when exposure occurred at 72 hpf compared to 7 dpf, suggesting the developing retina is more susceptible to long-term dysregulation of E 2 signaling by BPA

doi: 10.1007/s40261-023-01324-0

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However, too high of an exposure to GLP-1R for long time can lead to receptor desensitization, so finding the right balance is warranted