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93 (Suppl 1), S157S161 (2005)

GPx is one of the most-studied enzymes in cellular biology

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Unlike other forms of regulated cell death, ferroptosis does not rely on a single dedicated executioner protein but instead reflects the balance between pro-oxidant metabolic processes and multilayered defense systems that limit oxidative membrane damage

21 compounds were identified by mass spectrometry and ranked by their potential ability to inhibit ALOX-5 and HDC gene expression in silico, and suggested Luteolin as a strong candidate for modulation of mast cell activation

Another MC exposure experiment on cultures of Saccharomyces cerevisiae D7 strain showed increased frequency of gene conversions, reversions and mitotic combinations