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Unlike pharmaceutical drugs, which typically target a single pathway, herbal compounds act through multiple mechanisms, making it harder for fungi to adapt and develop resistance to them 37

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Epithelial integrity is related to E-cadherin expression, E-cadherin is a type I cadherin transmembrane glycoprotein coded by the CDH1 gene and forms the main structure of apical junctional complexes and the epithelial barrier [21]

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