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While several studies examined GPx activity [63, 71, 72, 74, 81, 83, 84] or its polymorphisms [94, 95], only one examined glutathione reductase or glutathione-S-transferase activity [85]
[11] It is important to note that the majority of mechanistic evidence derives from laboratory and animal studies rather than large-scale human clinical trials
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Activating pathways for creation of NADPH has been shown to protect RPE cells from oxidative damage 74 , and our findings indicate that for developing mouse retinas with RP in which all rods have been lost a possible intervention strategy would be to stimulate synthesis of NADPH
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The taste precursor molecules, trans S-1-propenyl-L-cysteine-sulfoxides isoallinin, are degraded by alliinase to create thiopropanal S-oxide (tear-causing factor), pyruvic acid, and ammonia
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