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Animal studies administering 5-Amino-1MQ orally to diet-induced obese mice have shown dose-dependent reductions in body weight (typically 10-30% reduction compared to vehicle-treated obese controls over 4-12 week treatment periods), with the weight loss primarily reflecting fat mass reduction while lean mass is preserved or even increased

NNMT inhibitor compound Class: Small-molecule NNMT (nicotinamide N-methyltransferase) inhibitor Formula / M.W.: C 10 H 11 IN 2 , ~286.11 g/mol (iodide salt)

Sparrow MP, Hande SA, Friedman S, et al

Along with a clean surface to work from, a thorough washing of your hands should become a habitual first step prior to handling your vial or ampule, syringe and needles

[3] The same work profiled shifts in the cecal microbiome associated with treatment

Nature Metabolism