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NGT, normal glucose tolerance
For oral semaglutide (Rybelsus), follow the strict administration requirements: take on an empty stomach when you first wake up, with no more than 4 ounces of plain water, and wait at least 30 minutes before eating, drinking, or taking other oral medications
Clinical trials with GLP-1 receptor agonists consistently demonstrate significant weight loss, with higher doses (such as semaglutide 2.4 mg weekly) producing approximately 15% average weight loss in adults without diabetes in clinical trials (somewhat less in type 2 diabetes) when combined with lifestyle modification
That means burning 200-300 fewer calories dailyeven if youre eating the same
Protein requirements Adequate protein intake becomes critical when losing weight on tirzepatide
Incretin Function A summary of physiological functions of GLP-1 and GIP is shown in Figure 9
