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494 Similarly, inhibition of the E3 ligase synoviolin suppresses synovial cell proliferation and reduces disease severity in RA models

Nonetheless, pharmacological therapeutic development for MAFLD based on the mechanisms of action, adverse events, and efficacy is reviewed and recommended in clinical practice guidelines (CPGs) issued by the liver international society in the Americas (AASLD), 6 Europe (EASL), 12 and Asia (APASL)

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11 , e2101202 (2022)