209 Endogenous GLP-1 has also been suggested to promote beta-cell proliferation in rodent cell lines and isolated rodent islet cells in addition to inducing apoptotic resistance
World J Hepatol
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Increasing the endogenous secretion of GLP-1 The apical surface of L-cells in the intestinal lining plays a critical role in sensing luminal compounds such as carbohydrates, proteins, gut microbiota, bacteria-derived molecules, bile acids, lipids, fatty acids, and polyphenols
They searched major medical databases for randomized controlled trials (RCTs) published between 2005 and April 2026, the period during which GLP-1RAs have been in use