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When cagrilintide is paired with semaglutide as CagriSema, the gap narrows23% for CagriSema versus 25.5% for Zepbound in a direct head-to-head trialbut Zepbound still holds a modest edge

The Pro-Gly-Pro tail was added to slow enzymatic breakdown so the molecule has a longer functional window than the bare ACTH fragment

Chen W-H, Xu X-D, Luo G-F, Jia H-Z, Lei Q, Cheng S-X, et al

CAS Number: 42464-96-0

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