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The authors acknowledge the scientific support of M
RNA, protein, and enzymatic evidence In the serum of 30 patients with bipolar depression, oxidant nitric oxide levels were increased while antioxidant SOD levels were decreased compared to healthy controls, suggesting that the ability to cope with oxidative stress is impaired in bipolar depression [83]
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However, when assessing EWcp/UCN1 dynamics in chronic alcohol consumption, we observed significant Ucn1 downregulation whereas the peptide content did not change, suggesting disrupted UCN1 turnover
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