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Without microneedles, permeation was near zero (Li et al

(PubMed) Ried K, Frank OR, Stocks NP

93 Impaired SIRT1 function decreases PPAR activity, leading to lipid metabolism disorders, increased hepatic lipid deposition, and aggravated inflammatory responses

Acknowledgements We thank the laboratory technicians in our animal unit at Novo Nordisk (Mlv, Denmark) for daily caretaking and for overseeing our experiments