Ample evidence indicates that optimising metabolic health and using renin-angiotensin system inhibitors and sodium-glucose cotransporter-2 (SGLT-2) inhibitors can delay the progression of DKD
That being said, its worth noting that GLP-1s may actually be beneficial for IBD patients who are stable, since weight loss can lessen inflammation, which can worsen symptoms of these conditions, Holly Lofton, MD, clinical associate professor of medicine and director of the Weight Management Program at NYU Langone Health, tells SELF
In a randomised controlled trial with over 1800 participants comparing tirzepatide to semaglutide, the tirzepatide group reported more serious adverse events (5-7% VS 3%) and higher discontinuation rates due to adverse events (6-8.5% VS 4%)
For injectable forms (like Ozempic or Wegovy), youll give yourself the shot just under the skin
Conclusions To summarize, the connection between metabolic and cognitive health highlights brain-body communication, redefining some disorders as neurometabolic
What Could Delay or Accelerate the Timeline