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The practical takeaway: Injection = high systemic distribution tendons, ligaments, muscle, joints, vascular tissue Oral = high local GI concentration intestinal lining, gastric mucosa, gut repair Nasal = intermediate systemic delivery potential neurological targeting, emerging evidence only Injectable BPC-157: Highest Bioavailability for Systemic and Musculoskeletal Goals Injectable BPC-157 is the best-studied delivery method for healing applications outside the gastrointestinal tract

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It also has a direct effect on the heart and endothelial cells, preventing the progression of atherosclerosis through mechanisms such as increasing nitric oxide and decreasing endothelin-1, reactive oxygen species, and inflammatory cytokines

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Magnesium can also act as a muscle relaxant, while calcium promotes muscle contraction, which can counteract each others effects