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J Biol Chem 283: 21347-21361 Dowdle J, Ishikawa T, Gatzek S, Rolinski S, Smirnoff N (2007) Two genes in Arabidopsis thaliana encoding GDP-L-galactose phosphorylase are required for ascorbate biosynthesis and seedling viability

It usually takes a glitch in your genetic code for this to happen and it typically takes decades