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In some cases, as in the treatment of hangovers, its an as-needed treatment to deal with an acute problem

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PIO also improved steatohepatitis indices

Free Radic Biol Med 66:3644 Ohno K, Ito M, Ichihara M, Ito M (2012) Molecular hydrogen as an emerging therapeutic medical gas for neurodegenerative and other diseases

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Since cortisol secretion also follows a regular circadian pattern roughly opposite to that of melatonin, this finding provides additional confirmation of possible day-night cycle disturbance in women with PCOS