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The authors suggested that given previous research that formononetin displays slower glucuronidation in intestinal and hepatic microsomes and higher gut permeability [127], formononetin bioavailability have benefited from its structural methylation status making it more liposoluble and improving permeability [126]

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A: Possibly, but evidence is limited

The removal of electrons from the catechin rings makes the hydroxyl bonds more acidic, so the hydroxyl bonds are organized to split two protons and function as a nucleophile

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