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A 2021 analysis in Menopause (the journal of the Menopause Society) found that GLP-1 receptor agonists reduced visceral adipose tissue in postmenopausal women independent of total weight loss, suggesting a mechanism beyond simple caloric restriction

Sudden loss of appetite suppression and delayed gastric emptying effects Central satiety signals diminish quickly Metabolic adaptations (reduced energy expenditure, increased hunger hormones like ghrelin) rebound sharply The underlying biology of obesity a chronic, relapsing disease reasserts itself Could gradual down-titration help

Challenging obesity: Patient, provider, and expert perspectives on the roles of available and emerging nonsurgical therapies

High IGF-1 levels have been linked to increased risk for gastrointestinal, prostate, ovarian and breast cancers (18, 19)

When will I start to see results