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Because meiotic arrest is closely linked to defects in spindle and chromosome structure and abnormalities in chromosome number, we performed a comprehensive analysis of these indicators in oocytes from all groups

Although basal levels of HGP were unchanged, insulin-stimulated HGP was significantly lower in HFHC-fed Dpp4 / (Figure 1C), resulting in a significantly greater suppression of HGP by insulin in Dpp4 / mice (Figure 1D)

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