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These procedures rapidly normalize glucose metabolism and enhance insulin secretion both before(Isbell et al., 2010) and after significant weight loss (Salehi et al., 2011)

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In certain instances, once exposure to an active agent (e.g., concentration in the endolymph or perilymph) reaches steady state, the concentration of an active agent in the endolymph or perilymph stays at or about the therapeutic dose for an extended period of time (e.g., one day, 2 days, 3 days, 4 days, 5 days, 6 days, 1 week, 3 weeks, 6 weeks, or 2 months)

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-H2AX, Phosphorylated form of Histone H2AX