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In another study, linagliptin effectively reduced hyperglycemia in Asian patients with uncontrolled T2DM, irrespective of age, body mass index, renal function, or ethnic subgroup, and was well tolerated [34]

"Useful work" here means literally anything you ask your body to do including muscle protein synthesis , neuromuscular adaptations that increase strength , and general recovery from exercise

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While the evidence base for GLP-1RAs continues to evolve, it remains unclear to what extent weight loss achieved during treatment explains or modifies CV risk reduction