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13 Dec 2022

Efficacy and safety profiles are equivalent

In this review, not only do the authors point to the usefulness of serum periostin as a TH2 biomarker but they also suggest that, at least in skin, periostin is crucial for amplification and persistence of allergic inflammation by communicating between fibroblasts and keratinocytes

The oral pill has strict timing rules: it is taken on an empty stomach with a little water, then you wait before eating or drinking

Her blood labs have been ordered and were all watching closely

The practical significance is that orforglipron may have a unique side effect profile and could potentially be combined with peptide-based GLP-1 agonists in future research, though no combination studies have been conducted