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Minot proposed that liver may be useful in the treatment of pernicious anemia, even though it was different than the anemia induced in Whipples dogs

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Two additional MTHFD1-related genes, MTHFD1L and MTHFD2L encode mitochondrial NADP + -dependent enzymes

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Generally yes at typical doses (up to 23 g/day), but some people experience stomach upset or a fishy odour

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