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The drug was first studied for Parkinson's and Alzheimer's disease because dopamine signaling matters in both

Importantly, semaglutide slows gastric emptying, which moderates post-prandial glucose excursions and promotes satiety

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It was FDA-approved based on phase 3 trials showcasing its potent hunger-suppressing and satiety-promoting effects, having been found to induce weight loss of 9.6%17.4% from baseline within 68 weeks in adults struggling with chronic weight issues [5]