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Serious adverse effects are rare but can include severe allergic reactions or exacerbation of existing health conditions

Mechanistically stabilization of the SnCE1 non-acetylated monomer might contribute to this effect of SnCE1 acetylation, as exemplified by the observation that monomeric, non-acetylated SnCE1 Y212A shows stronger processing compared to tetrameric, non-acetylated SnCE1 C256A and monomeric, acetylated wild type SnCE1 (Fig

Acta Crystallogr Sect F 70:11621166

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LD50 values gained from monkeys indicated that 880 grams applied on the skin or 320 grams injected intravenously would result in 50% mortality in 80 kg humans 7

Am J Physiol Cell Physiol 293(2):C584C596