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Notably, early studies demonstrated that 1,25(OH)D could inhibit the DNA-binding activity of NF-B in human MRC-5 fibroblasts without preventing the nuclear translocation of its p50 or p65 subunits

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However, the long-term effects on a patients health beyond the trial timelines and on the costs to the healthcare system are still uncertain

Miyashita A, Ito J, Parida IS, Syoji N, Fujii T, Takahashi H, et al

For individuals grappling with compulsive overeating, these medications can help disrupt the cycle of addiction-like behavior surrounding food

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