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Older individuals often have reduced nitric oxide production, stiffer blood vessels, and altered responses to vasoactive compounds

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Common side effects (GLP-1 medications) Nausea Vomiting Diarrhea or constipation Reduced appetite to the point of under-eating Rare but serious risks may include: Pancreatitis Gallbladder issues Growth hormone-related peptides Potential risks: Fluid retention Joint pain Insulin resistance (if misused) Long-term unknowns For newer or research peptides, long-term data is limited

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Sustain Mater Technol 29:e00322 Zhang H (2015) Ultrathin two-dimensional nanomaterials