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44 Thus, apart from tumor thickness greater than 5 mm and the presence of lymphovascular invasion, many of the histologic prognostic parameters of cutaneous melanoma (i.e., Breslows classification and Clarks level of invasion) do not apply to oral melanoma

Potential benefits include enhanced detoxification, reduced inflammation, improved immune function, and faster recovery times

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The choice of therapy now considers the patients clinical profile such as co-existing CV disease, renal disease or obesity

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