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Higher doses reached that plateau later in the trial. In a 112-week step-down trial, participants maintained 21.9% loss on the top dose, 16.6% after stepping down to 5 mg, and 9.9% on placebo
Key points: Formulation: Most commonly, cyanocobalamin or hydroxocobalamin in aqueous solution is used
Safety and Side Effects: Most side effects are mild and temporary
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It is also shown in animal models to bolster biochemical feedback mechanisms along the gut-brain axis [2, 4, 22]
This deficiency can be corrected with regular B12 injections from Pamela Phillips, Ph.D., FNP-C, and her team at Phillips Family Medical in DeSoto, Texas
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