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To explore T cell iron metabolism in lupus, researchers used CRISPR gene editing to assess iron-handling genes in T cells

For GST-EGFP-GPI CEAM7, the positive ratio was increased from 20% to 75% in K-562 and from 18% to 65% in Lenti-X 293T cells (Figure 3B)

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Exp Cell Res 226(2):336345 Deroanne CF, Lapiere CM, Nusgens BV (2001) In vitro tubulogenesis of endothelial cells by relaxation of the coupling extracellular matrix-cytoskeleton

The inclusion of GIP receptor agonism targets adipose tissue lipid metabolism, central appetite regulation through pathways distinct from GLP-1, and potentiation of insulin secretion through a separate intracellular signaling cascade

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