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, Investigators continue to explore how cagrilintide influences these pathways and whether sustained receptor activation produces distinct signaling effects compared with naturally occurring amylin

A dose-escalation approach was used, meaning participants started at a lower dose that was gradually increased over several weeks to reach the target dose

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Central Nervous System (CNS) Pathway Exploration PT-141 is employed in rodent models to study hypothalamic signaling, neuromodulation, and neuroendocrine axis regulation