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Herein, we overviewed the role of GIP and GLP-1 in the pathophysiology of type 2 diabetes and systematically reviewed the efficacy and safety of injectable incretin-based therapy added to basal insulin in light of the results of the SURPASS-5 trial

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Comparing Cagrilintide with GLP-1 receptor agonists allows researchers to examine how different peptide hormone pathways influence metabolic signaling, receptor pharmacology, and neuroendocrine regulatory mechanisms