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Zepbound (tirzepatide) studies generally show marginally better average weight loss outcomes compared to semaglutide at equivalent doses but Wegovy is highly effective, extensively studied, and costs the same copay on plans where it's preferred
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Liu Y, Yu Z, Zhao S, Cheng L, Man Y, Gao X, et al
doi: 23
Five mitochondrial enzymes are known to require lipoylation for catalysisthe PDHc, 2-oxoglutarate dehydrogenase complex (OGDHc), 2-oxoadipate dehydrogenase complex (OADHc), branched-chain -ketoacid dehydrogenase complex (BCKDHc) and the glycine cleavage system complex (GCVc)