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Wu AL, Moye-Rowley WS (1994) GSH1 , which encodes -glutamylcysteine synthetase, is a target gene for yAP-1 transcriptional regulation

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This dual action, increasing fat breakdown while simultaneously reducing new fat formation, has been observed in multiple rodent adipocyte models and provides a mechanistically distinct experimental profile compared to compounds that affect only one arm of fat metabolism

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