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The amino acid's role extends beyond simple neurotransmitter production to include thyroid hormone synthesis, where it serves as a backbone component for thyroxine (T4) and triiodothyronine (T3) formation

Medicare coverage depends on documented hypogonadism diagnoses supported by testosterone serum levels below 300 ng/dL, while commercial payers impose additional utilisation management protocols including step therapy and quantity limits

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However, understanding potential side effects helps with early identification and management

J Affect Disord 113:28590 Godman CA, Chheda KP, Hightower LE, Perdrizet G, Shin DG, Giardina C (2010) Hyperbaric oxygen induces a cytoprotective and angiogenic response in human microvascular endothelial cells